Enum FontFamily

const body =
    DocumentApp.getActiveDocument().getActiveTab().asDocumentTab().getBody();

// Insert a paragraph at the start of the document.
body.insertParagraph(0, 'Hello, Apps Script!');

// Set the tab font to Calibri.
body.editAsText().setFontFamily(DocumentApp.FontFamily.CALIBRI);

// Set the first paragraph font to Arial.
body.getParagraphs()[0].setFontFamily(DocumentApp.FontFamily.ARIAL);

// Set "Apps Script" to Comic Sans MS.
const text = 'Apps Script';
const a = body.getText().indexOf(text);
const b = a + text.length - 1;
body.editAsText().setFontFamily(a, b, DocumentApp.FontFamily.COMIC_SANS_MS);